Pranlukast-d5 960 HCl InChi: InChI=1S/C33H33ClN6O4/c1-35-31(42)27-17-21-6-10-25(11-7-21)37-32(43)28(39-33(44)29-14-15-36-40(29)2)19-24-18-23(9-12-26(24)34)22-5-3-4-20(16-22)8-13-30(41)38-27/h3-7

InChi: InChI=1S/C33H33ClN6O4/c1-35-31(42)27-17-21-6-10-25(11-7-21)37-32(43)28(39-33(44)29-14-15-36-40(29)2)19-24-18-23(9-12-26(24)34)22-5-3-4-20(16-22)8-13-30(41)38-27/h3-7

7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56

highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0

ERK and p38 following 24 h of co-treatment with Cisplatin (20 µM)

IDH-C227 was used at 1-5 µM final concentration in vitro

Pranlukast-d5 960 HCl InChi: InChI=1S/C33H33ClN6O4/c1-35-31(42)27-17-21-6-10-25(11-7-21)37-32(43)28(39-33(44)29-14-15-36-40(29)2)19-24-18-23(9-12-26(24)34)22-5-3-4-20(16-22)8-13-30(41)38-27/h3-7Pranlukast d5 (ONO 1078 d5) is the deuterium labeled Pranlukast. Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0. 63, 0. 99, and 5640 nM, respectively. Product information CAS Number: 1216719 50 4 Molecular Weight: 486. 53 Formula: C27H23N5O4 Chemical Name: N [4 oxo 2 (2H 1,2,3,4 tetrazol 5 yl) 4H chromen 8 yl] 4