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BS-181 HCl significantly inhibits cell migration and invasion ability in a dose-dependent manner
CAS Number: 950912-80-8
ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16
PubMed PMID: 17461215
JIB-04 (NSC693627
Corynoxine B spinesib (SB-715992) BS-181 HCl significantly inhibits cellCorynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin 1 dependent autophagy inducer. IC50 value: Target: Autophagy inducerin vitro: Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA, which may be attributed to its ability to block SNCA HMGB1 interaction . in vivo: Corynoxine B exhibited prolongation
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