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3 nM respectively
Solubility: DMSO : 50 mg/mL (173
(E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases
Smiles: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C
InChi: InChI=1S/C19H19ClN6O2/c1-11(22-19(28)18-8-17(12(2)27)23-24-18)10-26-6-5-16(25-26)13-3-4-14(9-21)15(20)7-13/h3-8
MT1 6727 3 nM respectivelyMT1 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0. 789 nM for BRD4(1). Product information CAS Number: 2060573 82 0 Molecular Weight: 1134. 20 Formula: C54H66Cl2N10O9S2 Chemical Name: 2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12 pentaen 9 yl] N (23 {2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12