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ALK3 or ALK6-induced Smad signaling
up to 100 mg/kg twice per day (formulated as a suspension in 0
2)10-16(23)18(14)19/h9
1988 Mar-Apr
2017 May 9
WY-135 Catalog No.:M28151-C ALK3 or ALK6-induced Smad signalingWY 135 is an ALK (IC50=1. 4 nM) and ROS1 (IC50=1. 1 nM) dual inhibitor. Product information CAS Number: 2163060 83 9 Molecular Weight: 612. 15 Formula: C28H34ClN9O3S Chemical Name: 5 chloro N2 (2 methoxy 4 {4 [(4 methylpiperazin 1 yl)methyl] 1H 1,2,3 triazol 1 yl}phenyl) N4 [2 (propane 2 sulfonyl)phenyl]pyrimidine 2,4 diamine Smiles: CN1CCN(CC2=CN(N=N2)C2=CC(OC)=C(C=C2)NC2=NC(NC3=CC=CC=C3S(=O)(=O)C(C)C)=C(Cl)C=N2)CC1 InChiKey: MYBIYOGYGXIDJG