S-(2-aminoethyl) Isothiourea (dihydrobromide) 684PADS tetrasodium 3E)-5-hydroxy-3-methylpenta-1

3E)-5-hydroxy-3-methylpenta-1

Solubility: DMSO : 125 mg/mL (1040

Smiles: CN1CCN(CC1)C1=CC(NC2C=C(C)NN=2)=NC(/C=C/C2C=CC=CC=2)=N1

CAS Number: 1037792-44-1

InChiKey: GPTXCAZYUMDUMN-UHFFFAOYSA-N

S-(2-aminoethyl) Isothiourea (dihydrobromide) 684PADS tetrasodium 3E)-5-hydroxy-3-methylpenta-1S (2 aminoethyl) Isothiourea (dihydrobromide) is a potent and non selective inhibitor of NOS with Ki values of 1. 8, 2. 1, and 0. 59 M for human nNOS, eNOS, and iNOS, respectively . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger. Nitric oxide synthase (iNOS, eNOS, and nNOS) catalyzed the production of NO in the two step oxidation of L