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Target: Histamine H1-receptorMizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis)
RS-127445 is found to has nanomolar affinity for the 5-HT2B receptor (pKi=9
Takeyama K
CAS Number: 33983-39-0
InChi: InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8
23-epi-26-Deoxyactein - CAS# 501938-01-8 3140 Target: Histamine H1-receptorMizolastine is a23 epi 26 Deoxyactein is a natural and orally active anti obesity and anti cancer compound. Product information CAS Number: 501938 01 8 Molecular Weight: 660. 83 Formula: C37H56O10 Chemical Name: (1R,1'R,2R,3'R,4'R,5R,5'R,6'R,10'S,12'S,13'S,16'R,18'S,21'R) 4',5,6',12',17',17' hexamethyl 18' {[(2S,3R,4S,5R) 3,4,5 trihydroxyoxan 2 yl]oxy} 3,6,9' trioxaspiro[bicyclo[3. 1. 0]hexane 2,8' hexacyclo[11. 9. 0. 0,. 0,. 0,. 0,]docosan] 3' yl acetate Smiles:
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