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Formula: C35H34F6N4O7
is a selective and cell permeable methyl-lysine binding protein 53BP1 antagonist with micromolar activity
1007/s00586-014-3675-2
BI-3663 inhibits PTK2 with an IC50 of 18 nM
ON-01910 is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity
M-110 0192 Formula: C35H34F6N4O7M 110 is a inhibitor of protein arginine N methyltransferases (PRMTs). It is also a highly isoform selective, cell permeable and potent ATP competitive inhibitor of the PIM kinase family that prefers PIM 3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0. 6 to 0. 9 M, with no activity on normal human peripheral blood mononuclear cells up to 40 M. Product information CAS Number: 1395048 49 3 Molecular Weight: 445.
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