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Okada-Iwabu
InChiKey: ZZVOPDBZUNUMPR-UHFFFAOYSA-N
37)14-22(36)31-9-11-35-10-8-20-23(35)24(33-15-32-20)34-17-6-7-21(19(27)13-17)38-18-5-3-4-16(12-18)26(28
Formula: C16H18ClN5O2
indicating that Syk kinase is the primary target of R112
β-Hydroxyisovalerylshikonin - CAS# 7415-78-3 te disodium Okada-IwabuBeta hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0. 7M and 1M for EGFR and v Src receptor, respectively. Beta hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell death in NCI H522 and DMS114 cells. Product information CAS Number: 7415 78 3 Molecular Weight: 388. 41 Formula:
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