Pyrimidine-indole hybrid Catalog No.:M34537-C L-Buthionine sulfoximine

L-Buthionine sulfoximine

MDA-MB-231 and BT-549 cells) treatment substantially reduces the LIF activation of STAT3

Formula: C32H37NO4

with an IC50 of 140 nM

Ochromycinone has anticancer and antimicrobial activity

Pyrimidine-indole hybrid Catalog No.:M34537-C L-Buthionine sulfoximinePyrimidine indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of tubulin. Pyrimidine indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule