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RG3039 (PF-06687859
Formula: C10H5F3N4O
962:229-244
Epub 2017 Dec 28
01) reduction in blood pressure compare to control[3]
Danusertib (PHA-739358) Catalog No.:M7725-10 RG3039 (PF-06687859Danusertib, also known as PHA 739358, is a small molecule 3 aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA 739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine threonine kinases, are important
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