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Degraders of wee1 kinase
The micronucleus test reveals no elevation in the frequency of micronuclei as compared to the control group
3-[4-(3-methylbut-2-enoxy)phenyl]-4-(2-methylpropyl)furan-2
Smiles: CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN2C(=O)CC[C@H](NC(=O)C3=NC=CC4=CC=CC=C43)C(=O)N21
20-hexakis({3-[(diaminomethylidene)amino]propyl})-3
Brigatinib 14066 Degraders of wee1 kinaseBrigatinib (AP 26113) is a highly potent and selective ALK inhibitor, with an IC50 of 0. 6 nM. Product information CAS Number: 1197953 54 0 Molecular Weight: 584. 09 Formula: C29H39ClN7O2P Chemical Name: 5 chloro N4 [2 (dimethylphosphoryl)phenyl] N2 {2 methoxy 4 [4 (4 methylpiperazin 1 yl)piperidin 1 yl]phenyl}pyrimidine 2,4 diamine Smiles: CN1CCN(CC1)C1CCN(CC1)C1C=C(OC)C(=CC=1)NC1N=C(NC2=CC=CC=C2P(C)(C)=O)C(Cl)=CN=1 InChiKey: AILRADAXUVEEIR
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