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BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308
The drug works by constricting the blood vessels in the nose
Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling
(2011) Cancer Res
In vitro sensitivity studies with BILN 2061 showed a decrease in affinity for proteases of genotypes 2 and 3 (K(i)
Glucocorticoid receptor agonist - CAS# 1245526-82-2 Catalog No.:M10731-2 BAG 956 has been shownGlucocorticoid receptor agonist, CAS No. 1245526 82 2, is a potent Glucocorticoid receptor agonist. Glucocorticoid receptor agonist acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2. 1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid like anti inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and