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Epub 2013 Sep 13
CAS Number: 775351-61-6
3-beta-D-glucan
BX912 blocks PDK1/Akt signaling in tumor cells and suppresses the anchorage-dependent growth of a variety of tumor cell lines (such as PC-3 cells) in culture or induces apoptosis
Sebolt-Leopold JS
ANI-7 EG1-COOH Epub 2013 Sep 13ANI 7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI 7 inhibits the growth of multiple cancer cells, and potently and selectively inhibits the growth of MCF 7 breast cancer cells with a GI50 of 0. 56 M. ANI 7 induces CYP1 metabolizing mono oxygenases by activating AhR pathway, and also induces DNA damage, checkpoint Kinase 2 (Chk2) activation, S phase cell cycle arrest, and cell death in sensitive breast cancer cell lines. Product