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5106–5117
Formula: C20H32BrClN2O2
Solubility: DMSO 87 mg/mL (198
3-hydroxy-acetaminophen is a metabolite of Acetaminophen
4 nM and antagonized NKB-induced Ca(2+) mobilization in HEK 293 cells stably expressing the hNK-3 receptor (HEK 293-hNK-3R) with an IC(50) = 18
TIC10 isomer nib (AMG-706) 5106–5117TIC10 isomer is an isomer and the "inactive version" of TIC10. TIC 10 isomer was introduced to the research community since it was structurally wrong assigned as the bioactive TIC 10 during early stage development of TIC 10 (now called ONC 201). TIC 10 isomer was found to be inactive, which did not reduce the viability of cancer cells. TIC 10 isomer may be used as a reference compound to compare with ONC 201. Product information CAS Number: 41276 02 2
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