(R)-Elagolix Size:Contact [email protected] for quotation 3 nM for PDGFRα

3 nM for PDGFRα

1-benzoxazin-2-ylidene)ethan-1-amine

InChi: InChI=1S/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2

Chemical Name: (4-{[(2S

Dehydrocurdione

(R)-Elagolix Size:Contact [email protected] for quotation 3 nM for PDGFRαElagolix is a highly potent, selective, orally active, short duration, non peptide antagonist of the gonadotropin releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRHin vitro: Elagolix is a short acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full