MK-8353 Catalog No.:M19981-C Smiles: CC1(C)CC(CN2CCN(CC2)C2=CC=C(C=C2)C(=O)NS(=O)(=O)C2=CC(=C(C=C2)N[C@@H](CSC2C=CC=CC=2)CCNC)S(=O)(=O)C(F)(F)F)=C(CC1)C1C=CC(Cl)=CC=1

Smiles: CC1(C)CC(CN2CCN(CC2)C2=CC=C(C=C2)C(=O)NS(=O)(=O)C2=CC(=C(C=C2)N[C@@H](CSC2C=CC=CC=2)CCNC)S(=O)(=O)C(F)(F)F)=C(CC1)C1C=CC(Cl)=CC=1

treatment of U-2 OS cells with Digoxin results in a dose-dependent decrease in CHIKV infection with a half-maximal effective concentration (EC50) of 48

Stachyose (oral gavage

2Sb/c2*5-1(3(7)8)2(6)4(9)10

but does not activate ASK1/JNK in Ramos cells

MK-8353 Catalog No.:M19981-C Smiles: CC1(C)CC(CN2CCN(CC2)C2=CC=C(C=C2)C(=O)NS(=O)(=O)C2=CC(=C(C=C2)N[C@@H](CSC2C=CC=CC=2)CCNC)S(=O)(=O)C(F)(F)F)=C(CC1)C1C=CC(Cl)=CC=1MK 8353 (SCH900353) is a potent, selective and orally available ERK1 2 inhibitor, with IC50s of 23. 0 nM and 8. 8 nM, respectively; MK 8353 has antitumor activity. Product information CAS Number: 1184173 73 6 Molecular Weight: 691. 84 Formula: C37H41N9O3S Chemical Name: (3S) 1 (2 {4 [4 (1 methyl 1H 1,2,4 triazol 3 yl)phenyl] 1,2,3,6 tetrahydropyridin 1 yl} 2 oxoethyl) 3 (methylsulfanyl) N {3 [6 (propan 2 yloxy)pyridin 3 yl] 1H indazol 5 yl}pyrrolidine