KRAS G12D inhibitor 1 - CAS# 2621928-43-4 563 hydrochloride Duocarmycin SA is a potent

Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM

De Jager R

1992 Feb-Mar

CAS Number: 6754-20-7

OC(C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)[N+]12CCCC1)(C1C=CC=CC=1)C1C=CC=CC=1

KRAS G12D inhibitor 1 - CAS# 2621928-43-4 563 hydrochloride Duocarmycin SA is a potentKRAS G12D inhibitor 1 (example 243) is a KRAS G12D inhibitor, with an IC50 of 0. 8 nM for KRAS G12D mediated ERK phosphorylation. Product information CAS Number: 2621928 43 4 Molecular Weight: 582. 64 Formula: C33H32F2N6O2 Chemical Name: 4 (2 {[(2R, 7aS) 2 fluoro hexahydro 1H pyrrolizin 7a yl]methoxy} 4 {3, 8 diazabicyclo[3. 2. 1]octan 3 yl} 8 fluoropyrido[4, 3 d]pyrimidin 7 yl) 5 ethynylnaphthalen 2 ol Smiles: