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Lactate-sulfate grown cells are insensitive to the Na+ ionophore
75% LDE225 cream in NBCCS patients was very well tolerated and caused BCC regression
Formula: C17H16F3N3O5S
a therapeutic agent
75(1):235-43
PRMT1-2e - Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor. CAS# 17328-16-4 279 Lactate-sulfate grown cells are insensitivePRMT1 2e, CAS No. 17328 16 4, is a potent, specific and cell permeable inhibitor of protein arginine methyltransferase 1 (PRMT1) with an IC50 ~1. 5 M. It has no activity against CARM1 and Set7 9 methyltransferases. It inhibits growth of MCF7a breast cancer cells (IC50 ~1. 97 M) and LNCaP prostate cancer cells (IC50 ~4. 49 M). It can attenuate androgen induced gene expression in LNCaP cells. Product information CAS Number: 17328 16 4 Molecular Weight: