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RVX-208 - BET Bromodomain Inhibitor. CAS# 1044870-39-4 60428 InChiKey: UZIATSFXNVOVFE-OAHLLOKOSA-N

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Description

InChiKey: UZIATSFXNVOVFE-OAHLLOKOSA-N

targeting Akt1

InChi: InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4

RS-1: a RAD51-Stimulatory compound enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

(2015) Cell Stem Cell 16(2):142-7

RVX-208 - BET Bromodomain Inhibitor. CAS# 1044870-39-4 60428 InChiKey: UZIATSFXNVOVFE-OAHLLOKOSA-NRVX 208, CAS No. 1044870 39 4, also known as Apabetalone, is a potent inhibitor of BET bromodomains. RVX 208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX 208 increases the production of ApoA I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL C, but the molecular target was not previously reported. RVX 208 may be a promising new approach to the treatment of

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