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CAS Number: 81686-22-8
selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM
LMK235 exhibits cytotoxity against chemo-resistant cancer cell lines in human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 ~0
24 μM for DYRK1B and DYRK1A respectively
AMD-3465 inhibits CXCL-12-induced growth in U87 and Daoy cells
WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 60033 CAS Number: 81686-22-8WAY 316606, CAS No. 1781835 02 6, is a novel potent and selective inhibitor of secreted frizzled related protein 1 (sFRP 1) with an IC50 ~ 0. 65 M. WAY 316606 prevents sFRP 1 from interacting with Wnt and thus increases Wnt signaling. WAY 316606 can increase total bone area in a murine calvarial organ culture assay. Product information CAS Number: 1781835 02 6 Molecular Weight: 484. 94 Formula: C18H20ClF3N2O4S2 Related CAS Number: 915759 45 4 (free