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TLQP-21 Size:Contact [email protected] for quotation 1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carbaldehyde

SKU: 52236656273

4.7
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Description

1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carbaldehyde

103(12):4729-34

24 μM for HCT116

S-methyl DM1 binds to tubulin with a Kd of 0

InChi: InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10

TLQP-21 Size:Contact [email protected] for quotation 1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carbaldehydeTLQP 21, a VGF derived peptide endowed of endocrine and extraendocrine properties, is a potent G protein coupled receptor complement 3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP 21=10. 3 M; human TLQP 21=68. 8 M). TLQP 21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP 21 is used for the research in regulation of nociception and other relevant physiologic functions. Product information CAS Number: 869988 94 3 Molecular Weight:

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