EP4 receptor antagonist 1 639SK2945 Masitinib demonstrates weak inhibition of

Masitinib demonstrates weak inhibition of Abl and c-Fms

Smiles: O=C(NC1C=CC=CC=1)N1CCN(CC1)C1=NC(=NS1)C1C=CC=CC=1

17-hexaene

CAS Number: 10567-21-2

Smiles: CC(C)(C)OC(=O)N1CCN(CC1)C(=O)CCCC(O)=O

EP4 receptor antagonist 1 639SK2945 Masitinib demonstrates weak inhibition ofEP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6. 1 nM and 16. 2 nM, respectively. IC50s >10 M for human EP1, EP2,and EP3 receptors. Product information CAS Number: 2287259 07 6 Molecular Weight: 458. 43 Formula: C23H21F3N4O3 Chemical Name: 4 [(1S) 1 ({4 [(1E) prop 1 en 1 yl] 1 {[4