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Further exploration of M₁ allosteric agonists: subtle structural changes abolish M₁ allosteric agonism and result in pan-mAChR orthosteric antagonism
Smiles: NCCNS(=O)(=O)C1=CC=C(Cl)C2=CC=NC=C12
33)/t16-/m1/s1
Solubility: Solubility (25°C) DMSO: 88 mg/mL(199
Solubility: H2O : 100 mg/mL (254
RA 2 Size:2mg solid Further exploration of M₁ allostericRA 2 is a pan negative gating modulator of KCa2 3 channels. It acts by inhibiting EDH type relaxation in coronary arteries. Product information CAS Number: 1867107 62 7 Molecular Weight: 414. 36 Formula: C22H16F2O6 Synonym: RA 2 Chemical Name: 1, 3 Phenylenebis(methylene) bis(3 fluoro 4 hydroxybenzoate) Smiles: OC1C=CC(=CC=1F)C(=O)OCC1C=C(COC(=O)C2C=C(F)C(O)=CC=2)C=CC=1 InChiKey: XOZKRECPKXTNAK UHFFFAOYSA N InChi: InChI=1S C22H16F2O6 c23 17 9 15(4 6
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