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FTI-2153 Catalog No.:M27128-C Smiles: COCCNC(=O)C1=CC=C(C=N1)OC1SC(C(N)=O)=C2CCC3C=NSC=3C2=1

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Description

Smiles: COCCNC(=O)C1=CC=C(C=N1)OC1SC(C(N)=O)=C2CCC3C=NSC=3C2=1

Formula: C13H7F6NO3S

2R)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]butanediamide

ultrasonic and adjust pH to 9 with NaOH) 0

CAS Number: 82989-21-7

FTI-2153 Catalog No.:M27128-C Smiles: COCCNC(=O)C1=CC=C(C=N1)OC1SC(C(N)=O)=C2CCC3C=NSC=3C2=1FTI 2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1. 4 nM. FTI 2153 is >3000 fold more potent at blocking H Ras (IC50, 10 nM) than Rap1A processing. Anti cancer activity. Product information CAS Number: 344900 92 1 Molecular Weight: 466. 60 Formula: C25H30N4O3S Chemical Name: methyl (2S) 2 {[5 ({[(1H imidazol 5 yl)methyl]amino}methyl) 2' methyl [1,1' biphenyl] 2 yl]formamido} 4

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