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PROTAC BRD4 Degrader-14 cinimide sodium ATP dipotassium induces the secretion

SKU: 55428675421

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Description

ATP dipotassium induces the secretion of IL-1β

6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer

LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity

CAS Number: 1279037-95-4

InChi: InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12

PROTAC BRD4 Degrader-14 cinimide sodium ATP dipotassium induces the secretionPROTAC BRD4 Degrader 14 is a PROTAC connected by ligands for von Hippel Lindau and BRD4, with IC50s of 1. 8 nM and 1. 7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader 14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. Product information Molecular Weight: 1150. 27 Formula: C57H61F2N9O11S2 Chemical Name: 8 (3,5 difluoropyridin 2 yl) N (2 {3 hydroxy 5 [2 ({[(2S) 1 [(2S,4R) 4 hydroxy 2 ({[4 (4 methyl 1,3

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