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PubMed PMID: 29441022
Combining PDMP and GNF-2 eliminated transplanted-CML-T315I-mutants in vivo and dose dependently sensitized primary cells from CML T315I patients to GNF-2-induced proliferation inhibition and apoptosis
Cell Physiol Biochem
Molecular Weight: 346
The mechanism lies in CGK733 triggers the formation of multinucleated cells thus promotes the premature mitotic exit of taxol-induced mitotic-damaged cells through multinucleation and mitotic catastrophe in HBV-positive HepG2
NVP-TAE684 - CAS# 761439-42-3 416 PubMed PMID: 29441022NVP TAE 684, CAS No. 761439 42 3, is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL derived and ALK dependent cell lines with IC50 values between 2 and 10 nM. Product information CAS Number: 761439 42 3 Molecular Weight: 614. 20 Formula: C30H40ClN7O3S Synonym: TAE684 Chemical Name: 5 chloro N4 (2 (isopropylsulfonyl)phenyl) N2 (2 methoxy 4 (4 (4 methylpiperazin 1 yl)piperidin 1 yl)phenyl)pyrimidine 2,4 diamine Smiles:
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