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Like nefopam
4-tetrahydroisoquinolin-2-yl]-N-methyl-2-phenylacetamide hydrochloride
1986 Jun 12-18
9(4):844-55
and good exposure in humans
Dehydrocorydaline 02 Hydrochloride Like nefopamDehydrocorydaline (13 Methylpalmatine) is an alkaloid isolated from traditional Chinese herb Corydalis yanhusuo W. T. Wang. Dehydrocorydaline regulates protein expression of Bax, Bcl 2; activates caspase 7, caspase 8, and inactivates PARP. Dehydrocorydaline elevates p38 MAPK activation. Anti inflammatory and anti cancer activities. Dehydrocorydaline shows strong anti malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P.