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DM1-PEG4-DBCO vothyroxine acyl glucuronide 6R)-5-{[(2S

SKU: 574021420

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Description

6R)-5-{[(2S

induces apoptosis and pro-death autophagy in A549 lung cancer cells

[Epub ahead of print] PubMed PMID: 25525863

is a Hydrolyzable linker for making ADC conjugate

AZM475271 remarkably inhibits growth and metastasis of orthotopically implanted human pancreatic carcinoma cells in nude mice

DM1-PEG4-DBCO vothyroxine acyl glucuronide 6R)-5-{[(2SDM1 (PEG)4 DBCO is a drug linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO PEG4 Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor specific delivery. Product information Molecular Weight: 1198. 79 Formula: C63H80ClN5O16 Chemical Name: [(2R,

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