Lp-PLA2-IN-3 235oosendanin InChi: InChI=1S/C23H23Cl2F2N5O3/c1-28-20(33)7-12-6-13(11-3-4-16(26)17(27)5-11)18(10-29-12)31-23(34)19-8-14(22(25)35-19)21-15(24)9-30-32(21)2/h3-5

InChi: InChI=1S/C23H23Cl2F2N5O3/c1-28-20(33)7-12-6-13(11-3-4-16(26)17(27)5-11)18(10-29-12)31-23(34)19-8-14(22(25)35-19)21-15(24)9-30-32(21)2/h3-5

is a potent inhibitor of aspartate transcarbamoyl transferase

the clonogenic capacity of LN18 cells exposed to TMZ in combination with 4-Diethylaminobenzaldehyde (DEAB) is significantly attenuated

1 nM and 5

In comparison to the vehicle treated group

Lp-PLA2-IN-3 235oosendanin InChi: InChI=1S/C23H23Cl2F2N5O3/c1-28-20(33)7-12-6-13(11-3-4-16(26)17(27)5-11)18(10-29-12)31-23(34)19-8-14(22(25)35-19)21-15(24)9-30-32(21)2/h3-5Lp PLA2 IN 3 is a potent and orally bioavailable lipoprotein associated phospholipase A2 (Lp PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp PLA2 (rhLpPLA2). Product information CAS Number: 2196245 16 4 Molecular Weight: 467. 85 Formula: C20H13ClF3N3O3S Chemical Name: 4 amino N {4 [4 chloro 3 (trifluoromethyl)phenoxy] 3 cyanophenyl}benzene 1 sulfonamide Smiles: NC1C=CC(=CC=1)S(=O)(=O)NC1=CC(C#N)=C(C=C1)OC1=CC(=C(Cl)C=C1)C(F)(F)F