4-Hydroxynonenal tyl-7-aminocephalosporanic acid is a highly potent and

is a highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM

while being less than 1% as active as the calcitriol in regulating calcium metabolism

Formula: C45H68F3N3O11

TG003 (10 μM) rescues the embryonic defects induced by excessive Clk activity in Xenopus

is a potent and selective IDH1 R132H inhibitor first reported in patent WO2012009678

4-Hydroxynonenal tyl-7-aminocephalosporanic acid is a highly potent and4 Hydroxynonenal (4 HNE) is an , unsaturated hydroxyalkenal and an oxidative nitrosative stress biomarker. 4 Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4 Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4 Hydroxynonenal plays an important role in cancer through