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A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways
InChiKey: RPAJWWXZIQJVJF-UHFFFAOYSA-N
which reduces dihydrofolate to tetrahydrofolate (THF)
Lanraplenib succinate inhibits IC-stimulated TNFα and IL-1β release (EC50=121±77 nM and 9±17 nM
is fusioninactive
TLR7/8 agonist 4 hydroxy-PEG10-acid Catalog No.:M17695-C A small-molecule inhibitor of UBE2NTLR7 8 agonist 4 hydroxy PEG10 acid (compound 9) is a drug linker conjugate for ADC with potent antitumor activity by using TLR7 8 agonist 4 (HY 139018; a TLR7 8 agonist), linked via the cleavable ADC linker hydroxy PEG10 acid (HY 133307). Product information CAS Number: 2388520 17 8 Molecular Weight: 837. 01 Formula: C41H68N6O12 Chemical Name: 1 (4 {4 amino 2 butyl 1H imidazo[4, 5 c]quinolin 8 yl}piperazin 1 yl) 3, 6, 9, 12, 15, 18, 21, 24, 27, 30