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Smiles: OC(=O)/C=C/C1=CC(Br)=C(Br)C(Br)=C1Br
14)/t4-/m0/s1
3-dihydropyridazine-4-carboxamides for the treatment of cancer
The extent of inhibition therefore correlated well with the expected free Quizartinib plasma levels
21 μM) over THR-α (EC50=3
O-Desmethyl gefitinib D8 Size:Contact [email protected] for quotation Smiles: OC(=O)/C=C/C1=CC(Br)=C(Br)C(Br)=C1BrO Desmethyl gefitinib D8 is a deuterium labeled O Desmethyl gefitinib. O Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information Molecular Weight: 440. 93 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 {3 [(2, 2, 3, 3, 5, 5, 6, 6
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