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GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold)
Formula: C52H76N4O12
CAS Number: 587841-73-4
InChi: InChI=1S/C35H49NO11/c1-8-36-16-32(17-41-3)22(38)13-23(43-5)35-21-14-33(40)24(44-6)15-34(47-18(2)37
MDL71782 hydrochloride
Naratriptan Hydrochloride - CAS# 143388-64-1 Catalog No.:M10095-2 GSK-25 maintains good selectivity againstNaratriptan is a selective 5 HT1 receptor subtype agonist for the treatment of migraine headache. Naratriptan binds with high affinity to human cloned 5 HT1B 1D receptors. Migraines are likely due to local cranial vasodilatation and or to the release of sensory neuropeptides (including substance P and calcitonin gene related peptide) through nerve endings in the trigeminal system. The therapeutic activity of AMERGE for the treatment of migraine
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