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GDC-0339 AD hydrochloride(x) IKKε and TBK1 are serine/threonine

SKU: 60158940967

4.9
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Description

IKKε and TBK1 are serine/threonine kinases which are highly homologous to one another and other IkB kinases (IKK-α and IKK-β)

it also is a prodrug of terbutaline

Formula: C24H31ClN6O2

3-dimethyl-1

SK-Hep-1 cells) induces cell apoptosis

GDC-0339 AD hydrochloride(x) IKKε and TBK1 are serine/threonineGDC 0339 is a potent, orally bioavailable and well tolerated pan Pim kinase inhibitor, with Kis of 0. 03 nM, 0. 1 nM and 0. 02 nM for Pim1, Pim2 and Pim3, respectively. GDC 0339 is discovered as a potential treatment of multiple myeloma. Product information CAS Number: 1428569 85 0 Molecular Weight: 465. 50 Formula: C20H22F3N7OS Chemical Name: 5 amino N {5 [(4R,5R) 4 amino 5 fluoroazepan 1 yl] 1 methyl 1H pyrazol 4 yl} 2 (2,6 difluorophenyl) 1,3

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