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NSC 664704
1-difluoroprop-2-yn-1-yl)-1-hydroxy-11a-methyl-10-{2'
24-pentakis(acetyloxy)-25-hydroxy-3
CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCN)C(C)(C)C)=CC=1
PubMed PMID: 24623980
AC-73 s34-IN-1 NSC 664704AC 73 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147 ERK1 2 STAT3 MMP 2 pathways. AC 73 inhibits the motility and invasion of hepatocellular carcinoma cells. AC 73 is also an anti proliferative drug and an inducer of autophagy in leukemic cells. Product information CAS Number: 775294 71 8 Molecular Weight: 319. 40 Formula:
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