Bafilomycin A1 Catalog No.:M12329-10 CAS Number: 21178-57-4

CAS Number: 21178-57-4

1-13H3/t19-

γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity

28 microM)

Formula: C28H33N5O4S

Bafilomycin A1 Catalog No.:M12329-10 CAS Number: 21178-57-4Bafilomycin A1 is a specific and reversible inhibitor of vacuolar H+ ATPase (V ATPase) with IC50 values of 4 400 nmol mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis. Product information CAS Number: 88899 55 2 Molecular Weight: 622.