Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Sep 11 - Sep 16
EC359 (100 nM
with 50 nM PU-H71 needed to significantly reduce the LPS dependent nitrite release
InChi: InChI=1S/C10H8N4O3S
Smiles: CC1=CC(=CC=C1OC1C=CN2N=CN=C2C=1)NC1=NC=NC2=CC=C(C=C21)C1=CC=C(CNCCS(C)(=O)=O)O1
ME-401(PWT-143) is a potent and selective inhibitor of P110δ with IC50 of 8
(S)-Lisofylline Catalog No.:M22422-C EC359 (100 nMLisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,