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CAS Number: 106372-55-8
Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF
19(2):245-52
thereby inhibiting pyrimidine synthesis
Smiles: CCCNC(=O)C1=NN=C2C(=CC=CC2=C1N)C1C(F)=CC=CC=1OC
AP-18 Size:Contact [email protected] for quotation CAS Number: 106372-55-8AP 18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 M Cinnamaldehyde with an IC50 of 3. 1 M and 4. 5 M for human and mouse TRPA1, respectively. AP 18 reverses complete Freund's adjuvant (CFA) induced mechanical hyperalgesia in mice. AP 18 attenuated 30 M AITC induced Yo Pro uptake in a concentration dependent manner, with an IC50 of 10. 3 M. Product information CAS Number: 55224 94 7 Molecular Weight: 209. 67 Formula:
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