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Note: PF-562271 benzesulfonate is also called PF-562271 besylate
Allopurinol is a structural isomer of hypoxanthine
CAS Number: 24219-97-4
The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants
is a potent inhibitor of the CK1 isoforms CK1ε and CK1δ (IC50 = 7
ASP3026 D17-109 Note: PF-562271 benzesulfonate is alsoASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase activity and was more selective than crizotinib in a Tyr kinase panel. In an anchorage independent in vitro cell growth assay, ASP3026 inhibited the growth of NCI H2228, a human NSCLC tumor cell line endogenously expressing EML4 ALK variant 3 and that of 3T3 cells expressing EML4 ALK variant 1, 2 and 3. The plasma and tumor concentrations of ASP3026 in
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