D5D-IN-326 Catalog No.:M24172-C Smiles: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC1=NC2=CC(/C=C/C(=O)NO)=CC=C2N1CCN(CC)CC

Smiles: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC1=NC2=CC(/C=C/C(=O)NO)=CC=C2N1CCN(CC)CC

manifested by lengthening of the P-R interval and A-V block

5 and 10 mM glucose

10: 161–167

CAS Number: 1383716-33-3

D5D-IN-326 Catalog No.:M24172-C Smiles: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC1=NC2=CC(/C=C/C(=O)NO)=CC=C2N1CCN(CC)CCD5D IN 326 is a selective, orally active delta 5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell based assays, respectively, has no effect on D6D or D9D activity. D5D IN 326 reduces insulin resistance and decreases body weight in diet induced obese C57BL 6J mice. Product information CAS Number: 1236767 85 3 Molecular Weight: 473. 27 Formula: C17H11F8N3O4 Chemical Name: 2 (2,2,3,3,3 pentafluoropropoxy) 3