PF-06700841 an) a novel intracellular Ca2+ handling

a novel intracellular Ca2+ handling modulator that acts through reverse-mode Na+/Ca2+ exchanger inhibition and potential sarcoplasmic reticulum (SR) Ca2+ uptake enhancement

Chemical Name: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1

and stimulate fatty acid oxidation

20 and 40 mg/kg

potent and selective antagonist of leukotrienes

PF-06700841 an) a novel intracellular Ca2+ handlingPF 06700841 is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. PF 06700841 also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6. 49 M, respectively. Product information CAS Number: 1883299 62 4 Molecular Weight: 389. 40 Formula: C18H21F2N7O Chemical Name: 4 [(1R,5S) 8 [(1S) 2,2 difluorocyclopropanecarbonyl] 3,8 diazabicyclo[3. 2. 1]octan 3 yl] N (1 methyl 1H pyrazol 4 yl)pyrimidin 2 amine Smiles: