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It is developed as an anticancer agent
InChiKey: MUOKSQABCJCOPU-UHFFFAOYSA-N
5-Dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine (RO1138452) is a selective
Tsigelny I
It displays >17-fold selectivity for 53BP1 as compared to other methyl-lysine (Kme) binding proteins tested
BIBF 1120 - CAS# 656247-17-5 Catalog No.:M10935-2 It is developed as anNintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptor (PDGFR). Intedanib selectively binds to and inhibits vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptor (PDGFR) tyrosine kinases, which may result in the
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