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MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A
but it does not change the enzyme activity in vitro
CBL-C137 hydrochloride
URMC-099 is an orally bioavailable
2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene
Aspartame-d5 )-N-Biotin-PEG4-acid MMAF (Monomethylauristatin F) is widelyProduct information CAS Number: 1356849 17 6 Molecular Weight: 299. 33 Formula: C14H18N2O5 Chemical Name: (3S) 3 amino 3 {[(2S) 1 methoxy 1 oxo 3 [(2,3,4,5,6 H)phenyl]propan 2 yl]carbamoyl}propanoic acid Smiles: [2H]C1=C(C[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)OC)C([2H])=C([2H])C([2H])=C1[2H] InChiKey: IAOZJIPTCAWIRG HEPISUNPSA N InChi: InChI=1S C14H18N2O5 c1 21 14(20)11(7 9 5 3 2 4 6 9)16 13(19)10(15)8 12(17)18 h2 6,10 11H,7 8,15H2,1H3,(H,16,19)(H,17,18)