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7α-Hydroxy-4-cholesten-3-one Catalog No.:M26243-C Derazantinib inhibits FGFR1 and FGFR2

SKU: 6831369067

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Description

Derazantinib inhibits FGFR1 and FGFR2 mutants associated with craniosynostoses

Chemical Name: 2-{[1-(4-phenoxyphenoxy)propan-2-yl]oxy}pyridine

30 and 100 mg/kg oral dosing in combination with temozolomide (TMZ) in the mouse melanoma B16-F10 isograft model

InChi: InChI=1S/C5H8N2O5/c6-2(4(9)10)1-7-3(8)5(11)12/h2H

Formula: C27H23FN4O4S

7α-Hydroxy-4-cholesten-3-one Catalog No.:M26243-C Derazantinib inhibits FGFR1 and FGFR27 Hydroxy 4 cholesten 3 one is an intermediate in synthesis of bile acids from cholesterol. 7 Hydroxy 4 cholesten 3 one is a pregnane X receptor (PXR) agonist. 7 Hydroxy cholest 4 en 3 one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7 Hydroxy cholest 4 en 3 one is the physiological substrate for CYP8B1. Product information CAS Number: 3862 25 7 Molecular Weight: 400.

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