BI-1347 ozopran 3-d]pyrimidin-6-yl)-2-fluoroethan-1-one

3-d]pyrimidin-6-yl)-2-fluoroethan-1-one

including colorectal (HCT-116)

InChi: InChI=1S/C9H5ClN4/c10-7-2-1-3-8(4-7)13-14-9(5-11)6-12/h1-4

3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide

week 2 to 6 after BDL) attenuates bile ductular proliferation and peribiliary collagen deposition by 40-50%

BI-1347 ozopran 3-d]pyrimidin-6-yl)-2-fluoroethan-1-oneBI 1347 is a potent CDK8 inhibitor extracted from patent WO2017202719A1, product I 003, has an IC50 of 1. 1 nM. Product information CAS Number: 2163056 91 3 Molecular Weight: 356. 42 Formula: C22H20N4O Chemical Name: 2 {4 [4 (isoquinolin 4 yl)phenyl] 1H pyrazol 1 yl} N,N dimethylacetamide Smiles: CN(C)C(=O)CN1C=C(C=N1)C1C=CC(=CC=1)C1=CN=CC2C=CC=CC=21 InChiKey: WULUGQONDYDNKY UHFFFAOYSA N InChi: InChI=1S C22H20N4O c1 25(2)22(27)15 26 14 19(12 24 26)16