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ZCL278 abolished microspike formation and disrupted GM130-docked Golgi structures
as well as its association with HIF-1α
Rosiglitazone Maleate is a potent and selective activator of peroxisome proliferator-activated receptor gamma (PPAR gamma)
thus attenuating phosphorylation of the Aurora substrate H3S10
It incorporates an E3 ligase ligand plus a PEG4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand It is part of a range of functionalized tool molecules for PROTAC R&D
Tenofovir alafenamide hemifumarate tegravir (MK-0518) ZCL278 abolished microspike formation andTenofovir alafenamide (TAF, GS 7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV 1 infection. Product information CAS Number: 1392275 56 7 Molecular Weight: 1069. 00 Formula: C46H62N12O14P2 Synonym: Tenofovir alafenamide fumarate (2: 1) Chemical Name:
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