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Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C ) inhibits tumor growth

SKU: 70165967152

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Description

) inhibits tumor growth

InChi: InChI=1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8

6 and 1 μM respectively

Smiles: C[C@]12C[C@]3(C[C@H]1CCC[C@@H]2C)C(=C)COC3=O

InChi: InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H

Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C ) inhibits tumor growthDual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP C 4, which is CRBN based dual PROTAC for simultaneous degradation of EGFR and PARP. Product information Molecular Weight: 1020. 52 Formula: C53H56ClF2N9O8 Chemical Name: 6 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6

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