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Chemical Name: (3S)-3-(4-{[5-({spiro[indene-1
0 pM (-pIC50±SEM: 10
26(2):158-9
is a potent inhibitor of class I PI3K kinases with an IC50 of 19 nM
4]triazin-4(1H)-one dihydrochloride trihydrate
Atrasentan Hydrochloride K inhibitor 4 (trans) Chemical Name: (3S)-3-(4-{[5-({spiro[indene-1Atrasentan, also known as ABT 627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin induced angiogenesis and tumor cell proliferation. Product information CAS Number: 195733 43 8 Molecular Weight: 547. 08 Formula: C29H39ClN2O6 Chemical Name: (2R,3R,4S) 4 (2H
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