K-756 opam hydrochloride Pregnenolone likely acts as a

Pregnenolone likely acts as a signaling-specific negative allosteric modulator binding to a site distinct from that occupied by orthosteric ligands

ClH/c1-30-20-13-18(14-21(31-2)22(20)32-3)27-24-26-15-17-9-11-29(23(17)28-24)19-8-4-6-16(12-19)7-5-10-25

1994 Dec 1

InChiKey: SUJJACDTWCALRH-UHFFFAOYSA-N

100 uM) is able to overcome

K-756 opam hydrochloride Pregnenolone likely acts as aK 756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP ribosylation activity of TNKS1 and TNKS2 with IC50s of 31 and 36 nM, respectively. Product information CAS Number: 130017 40 2 Molecular Weight: 433. 50 Formula: C24H27N5O3 Chemical Name: 3 {[1 (6,7 dimethoxyquinazolin 4 yl)piperidin 4 yl]methyl} 1,2,3,4 tetrahydroquinazolin 2 one Smiles: COC1=CC2=NC=NC(=C2C=C1OC)N1CCC(CN2CC3C=CC=CC=3NC2=O)CC1 InChiKey: GWXCGEJJQFHPPA