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DOV-216, 303 Free Base cin M1 fluoroquinolones and/or ethambutol

SKU: 72293902887

4.7
USD100.00 USD141.00

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Ships within 48 hours · Estimated delivery Sep 10 - Sep 15

Description

fluoroquinolones and/or ethambutol

good bioavailability (55%)

T-βMCA sodium inhibits FXR reporter activity in the CRC cell line HT29 (EC50 ~10 μM)

COX-2-IN-2 shows no COX-1 inhibition even at 100μM

29-10-15-32(42)16-11-29)47(36)37(49)46-20-18-44(19-21-46)27-35(48)45-22-24-50-25-23-45/h8-17

DOV-216, 303 Free Base cin M1 fluoroquinolones and/or ethambutolDOV 216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats. Product information CAS Number: 66504 40 3 Molecular Weight: 228. 12 Formula: C11H11Cl2N Chemical Name: 1 (3,4 dichlorophenyl) 3

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